Hilton Head Island, off the south coast of South Carolina, is set in one of the cleanest estuaries on the whole East Coast. The largest island between New Jersey and Florida, this resort boasts 25 golf courses, 300 tennis courts and many other sporting facilities, and hosts the PGA Classic – the Heritage of Golf. Wildlife reserves include Pinckney Island National Wildlife Refuge, while history enthusiasts can visit the ruins of an original sea island cotton plantation. Harbour Town stands in the shadow of its distinctive red and white lighthouse.